Jardiance Tablet – Know Its Uses, Benefits, Interaction, Precautions, and Side Effects 

Medically Reviewed By: Dr. Mohammad Suleman Hussain, M.B.B.S February 19, 2024

Last updated on July 28th, 2023


Diabetes is a severe condition and can lead to severe health issues in the body over some time. Considering it can affect the overall working of the organs of the body. People who have type 2 diabetes need to be even more careful. Inadequately managed blood sugar can result in a variety of health issues. Therefore with the help of medicines such as Jardiance and lifestyle changes, one can control diabetes, and with proper diet and exercise, one can even reverse it.

As per studies, it is proven that diabetes results from poor lifestyle choices and a bad diet. It is one of the most common lifestyle diseases affecting millions of people and has a record of claiming several lives every year. It is a proven fact that the longer you have been affected by diabetes, the higher the risk of complications. Therefore, it becomes mandatory that you connect with a doctor and take the proper medication to control it.

Jardiance Tablet – Know Its Uses, Benefits, Interaction, Precautions, and Side Effects 

What is Jardiance?

Jardiance (empagliflozin) is an oral diabetes medicine that helps control blood sugar levels. Jardiance belongs to the SGLT-2 inhibitors drug class. As per surveys and experts, jardiance is called the double-duty drug prescribed to reduce the risk of cardiovascular death in adult patients diagnosed with both type 2 diabetes and cardiovascular diseases.

Why is Jardiance Called a ‘Double Duty’ Drug?

People who need medicine like Jardiance to control diabetes, often with specific lifestyle and dietary changes, get their cells in the bodies activated to produce insulin and regulate blood sugar levels. FDA has approved this medicine, and it was done after studies were done on more than 700 patients who had both conditions.

It is proven that type 2 diabetes patients always face certain long-term complications due to medical conditions. Thus it is essential to reverse the issue or control it. Most importantly, people with diabetes Type 2 have more risk of getting affected by cardiovascular disease, and thus, the condition could prove fatal. The study conducted by the National Institutes of Health indicates that death from cardiovascular disease is 70% higher in patients who have Type 2 diabetes. Therefore the medicine Jardiance is helpful in both cases.

Also Read: Glycomet Diabetes Medication

 Dosage Information:

The initial dose of the medicine for an adult is 10 mg orally once a day in the morning. Then, it could be increased to 25 mg orally if the patient requires additional hypoglycemic control. The maximum prescribed dose in a day is 25 mg per day.

How Jardiance Can be Helpful?


Blood sugar is the amount of glucose or simple sugar in the blood. Glucose is the primary source of energy for the body. Jardiance is a drug known as a sodium-glucose cotransporter-2 inhibitor (SGLT). Initially, the FDA agreed on it as a diabetes drug when used with diet and exercises to improve blood sugar levels in adults with type 2 diabetes.

Jardiance is not a magic pill, but it requires dedication, diet, and lifestyle changes to reverse type 2 diabetes. Only FDA-approved medicines like Jardiance or methods should be followed and adapted to reverse type 2 diabetes.

After a study was done on 7000 patients, it was seen that their A1C was between 7 to 10 percent. The researchers prescribed either 10 milligrams or 25 milligrams or a placebo pill daily for three years in a pattern of half long and half less. The patients are on other medicines to control cardiovascular disease and cholesterol. The research was conducted to understand the importance of treatment in lowering the death rate. Also, the test was understood as the utility of medicine in reducing the risk of non-fatal heart attack or brain stroke.

From the study, it was evident that Jardiance is prescribed explicitly for people with type 2 diabetes. According to the NIH, people who are consuming the pill for regular 24 weeks had the following results after the period:

  1. Hemoglobin A1c (HbA1c) levels are lowered by 0.7% to 0.8%.
  2. Fasting blood sugar levels are lowered by 19 mg/dl to 25 mg/dl.
  3. Bodyweight got reduced by 2.8 percent to 3.2 percent from their starting weight.

Benefits of Jardiance:

  • It is known to reduce blood sugar in adults with type 2 diabetes when taken with the proper diet and exercise schedule.
  • According to the FDA, Jardiance can reduce the risk of cardiovascular death in adults who also have type 2 diabetes.
  • Reduce the risk of heart failure and hospitalisation due to heart failure.

Jardiance is an effective medicine when combined with other diabetes medications. It is effective when combined with Metformin, insulin, glipizide, and pioglitazone. Overall, Jardiance reduced the death rate by 38% in cardiovascular and Type 2 diabetes people.

Also Read: Glycomet Trio 2 Uses and Composition

Mechanism of Jardiance:

Jardiance works by blocking the reabsorption of excess glucose by the kidney, leading to the excretion of more glucose in the urine. Thereby it works by helping the kidney get rid of glucose from the bloodstream. One can consume Jardiance with or without food as per the doctor’s instruction.

Also Read: Can Quitting Smoking Reverses Diabetes?

Important Safety Information:

Jardiance is a very effective medicine and works wonders for patients with Type 2 diabetes and cardiovascular issues. However, in some instances, the same drug can cause more harm than good; thus, it is crucial that one consumes it with all the safety precautions.

In certain situations, the patients are not prescribed Jardiance. The conditions are as follows:

  • According to MedlinePlus, Jardiance (Empagliflozin) is not for people with Type 1 diabetes as it could increase their risk of diabetic ketoacidosis.
  • According to the Mayo Clinic, people with Type 2 diabetes but with severe kidney issues have not been prescribed this pill as it will fail to work.
  • If the patient is allergic to empagliflozin or any other ingredients in Jardiance.
  • People on dialysis are not prescribed Jardiance as it will fail to work.
  • If the patient is scheduled for surgery, Jardiance is stopped to start again. It is mandatory to consult the doctor.
  • According to the NHS, pregnant and lactating women are not prescribed Jardiance, as it could harm the fetus and the newborn.
  • If the patient intends to get pregnant, consuming Jardiance is prohibited.
  • If the patient drinks alcohol regularly.
  • Inform the doctor if you consume any herbal supplements, vitamins, or over-the-counter medicines.
  • If the patient is swallowing any water pills (diuretics) or any other medication like insulin which can lower the blood sugar.
  • The patient is 65 or older
  • If the patient is on a low-salt diet.

Also Read: Tenglyn M 500 Tablet Uses, Side Effects, Dosage and Safety Advice!

Side effects of Jardiance:

Side effects of Jardiance:

Jardiance could result in specific mild side effects. However, one could reach out to an expert and remedy the side effects. The side effects are a burning sensation while urinating or frequent urinating. Another common side effect is vaginal yeast infection, with itching, soreness, and pain while urinating. The doctor could treat the side effects or consume over-the-counter medicines to cure the ailment.

1. Serious side effects:

Apart from the common side effects, there are severe specific side effects of Jardiance, resulting in other medical conditions if left untreated. Therefore, consulting the doctor is mandatory if the patient experiences any severe issues.

Serious side effects of Jardiance consumption are mostly not there, but then one could experience them, and for this, it is advised to connect with the doctor. According to the NHS, a few of the severe side effects and symptoms are as follows:

  • Hypotension (low blood pressure) symptoms are as follows:
  • Lightheaded
  • Falling when standing up
  • Dizziness
  • Clammy skin
  • Loss of consciousness
  • Depression

2. Kidney damage

3. Serious allergic reactions

  • Swelling of face or lips or any other areas of skin
  • Difficulty in swallowing
  • Difficulty in breathing
  • Red areas on skin hives

4. Severe infection near the genitals

  • Pain, redness, swelling in the skin around the genitals
  • Vaginal yeast infection
  • Yeast infection in the penis
  • Fever 
  • Weakness

5. Severe urinary tract infection

  • Burning sensation while passing urine
  • Pain in the lower part of the stomach
  • Blood in urine

Jardiance and Metformin

Jardiance is combined with Metformin to reduce blood sugar levels. Metformin is another prevalent drug for diabetes control. However, the two, when used together, can prove very effective. Metformin comes as a tablet or syrup, and both medicines are meant for oral consumption.

Also Read: Know Metformin Hydrochloride Tablet Uses, Side Effects, Interactions, Dosage and Precautions

FAQs (Frequently Asked Questions):

What other drugs will affect Jardiance?

Other drugs may either increase or decrease the effects of Jardiance on lowering blood sugar. Importantly, if you consume any other pill like insulin to control blood sugar, inform the doctor about it.

If one consumes Jardiance regularly, will they get habituated to it?

The best aspect of this anti-diabetic medicine is that you will not get habituated to it even when taken by cardiovascular-related issues. It is an effective medicine to regulate blood sugar levels. There are certain precautions and side effects of the tablet which can be easily monitored and managed. In some instances, it was observed that with a regulated diet and disciplined lifestyle, people could reverse their diabetes even when they had started consuming Jardiance tablets.

Can Jardiance tablets cause low blood sugar levels?

Yes, Jardiance can cause low sugar levels or hypoglycemia. It is one of the significant side effects of the tablet as it is given with Metformin, but then it occurs very rarely. Thus it gets mandatory that you regularly consult the doctor and check your blood sugar levels and ascertain if they are falling or not. If you are on the medicine very diligently, you should have low blood sugar levels. Some of the common symptoms of low blood sugar are dizziness, sweating, headache, and shaking. However, the medicine is worthwhile and primarily unavoidable; thus, always carry a fast-acting juice of glucose content like any fruit or sugar juice to help you avoid the side effect.

What if one forgets to consume the Jardiance tablet?

If you have missed one dose of the medicine, it is recommended that you consume it as soon as possible. However, if it is almost your next dose, skip the missed dose and shift to the next regular dose. Never should the amount be doubled. However, if you feel any problem, you should immediately consult the doctor.

Can type 2 diabetes result in an increased risk of cardiovascular diseases?

Blood sugar, if not controlled and managed in the long run, can damage the arteries. Diabetes causes an increase in the triglycerides and LDL cholesterol which are bad cholesterol and clog the arteries leading to a heart attack. People who have cardiovascular issues coupled with diabetes are more prone to die.

Is it important to consult a doctor and consume Jardiance?

Yes, going by the several kinds of research done in all parts of world, consulting a doctor regularly showed significant improvement in their blood sugar levels. The health expert prescribes Jardiance, which the FDA approves, which can help control blood sugar levels. However, it is not only medicine but lifestyle changes and dietary restrictions that further help in curing the disease. With the help of your physician, you can understand that what diet or lifestyle changes are helping you control your sugar levels.

Which foods should be for type 2 diabetes patients for better results from Jardiance as per FDA recommendation?

Sugar-loaded foods like soda, canned juices, sweets, and desserts are prohibited for diabetes patients. These foods are also banned for people with heart issues or who want to live a healthy life. Natural sweeteners like honey or cane sugar are also prohibited. Alcohol and smoking can affect blood sugar levels and conflict with the medicines; thus, they need to be avoided. Therefore they should be avoided.

Last Updated on by Dr. Damanjit Duggal 


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