Tenglyn M 500 Tablet Uses, Side Effects, Dosage and Safety Advice!

Medically Reviewed By: Dr. Surajeet Kumar Patra, MBBS, MD, FDIAB, MBA & APMP January 11, 2022

Last updated on July 28th, 2023

Tenglyn M 500 Tablet belongs to the class of drugs known as ‘antidiabetic agents,’ used to treat Type 2 diabetes. In diabetic patients who do not respond well to Metformin alone, this drug improves glycemic control. Diabetes mellitus type 2 is a long-term or chronic disorder in which blood sugar levels rise above normal. It occurs when the body does not create enough insulin (which metabolizes glucose) or when the insulin produced is ineffective.

Tenglyn M 500 Tablet is a drug that combines two medications: Metformin and teneligliptin. Metformin belongs to the ‘biguanides’ class of drugs, and it works by lowering liver glucose synthesis and intestinal glucose uptake. On the other hand, Teneligliptin acts by inhibiting the dipeptidyl Peptidase 4 enzyme, which boosts insulin levels while decreasing glucagon levels in the body. All of these acts help to lower blood sugar levels.

tab tenglyn m 500 tablet

The tenglyn m 500 Tablet is a tablet that can be taken orally. You must take this medication exactly as directed by your doctor. You may experience side-effects of such as vomiting (falling sick), nausea (feeling sick), diarrhea, stomachache, headache, respiratory infection, weight gain, palpitations, sweating, and vision problems. Some individuals have low blood sugar levels (hypoglycemia), which can cause sweating, dizziness, headaches, disorientation, hunger, transitory visual changes, restlessness, irritability, and weakness. In such circumstances, get medical help right once.

If you are allergic to any of the ingredients in the tenglyn m 500 Tablet, do not take it. If you have bladder cancer, heart failure, or diabetic ketoacidosis, you should not use this medication (a complication of diabetes). It can cause lactic acidosis (a build-up of lactic acid in the blood), which necessitates medical intervention very away. If you’ve previously been diagnosed with kidney or liver illness, you’re at a higher risk. Consume no alcohol (risk of lactic acidosis) or fast for extended periods (risk of hypoglycemia). Also, inform your doctor if you are planning to become pregnant, are pregnant, or breastfeeding.

Also Read: Galvus Met 50/500 MG Tablet Uses

Medicinal Benefits Tenglyn M 500 Tablet


Tenglyn M 500 Tablet is recommended for type 2 diabetes control when combined with a healthy diet and regular exercise. The tenglyn m 20 500 Tablet is used in combination with Metformin in people who cannot control their diabetes with Metformin alone. 

This medication improves the body’s insulin sensitivity and helps it return to normal. Metformin tablets should be taken regularly to allow the drug to release slowly in the body.

Directions for Use


Tenglyn M 500 Tablet is available in the form of tablets. Usually, your doctor may suggest the lowest dose; after that, the doctor will measure the blood sugar levels and adjust the dose. 

Tablets: Tenglyn m 500 tablets are to be swallowed as a whole with a glass of water. Do not chew, crush or break the tablets. Take the dose as per the prescription of your doctor at a fixed time every day. The doctor may advise you to take it once a day as it is available in the extended-release form.

Also Read: Metformin Hydrochloride Tablet Uses

Side Effects of Tenglyn M 500 Tablet

  • Nausea (feeling sick)
  • Vomiting (falling sick)
  • Diarrhea
  • Headache
  • Stomach ache
  • Respiratory infection
  • Weight gain
  • Sweating
  • Palpitations
  • Numbness
  • Vision problems

In-Depth Precautions and Warning


In people with heart problems, Tenglyn M 500 Tablet should be used with caution because it raises the risk of heart failure. It can produce lactic acidosis, characterized by abdominal pain, muscle cramps, vomiting, severe exhaustion, and difficulty breathing. 

It’s a life-threatening ailment that needs to be treated right away. Tell your doctor if you have any serious liver or kidney problems since proper liver and kidney function is required to clear excess lactic acid from the body. Excessive alcohol consumption raises the risk of lactic acidosis. Tenglyn 500 m Tablet may lower vitamin B12 levels, so it is recommended to take blood tests regularly to identify any vitamin deficiencies.

Also Read: Janumet 50 mg / 500 mg Tablet

When Should You Be Cautious While Using Tenglyn M 500 Tablet

  • Alcohol

Alcohol might alleviate the risk of side effects and worsen the condition.

  • Pregnancy

Tenglyn M 500 Tablet is a category C medicine, which means it can harm an unborn infant. As a result, it’s only utilized when the benefits of the medication outweigh the risks. Therefore, it is highly advisable for pregnant women to consult their doctor while consuming this tablet.

  • Breastfeeding

Tenglyn M 500 Tablet should not be used in breastfeeding mothers as it may get secreted in the breast milk and cause unwanted effects in the nursing babies. Breastfeeding mothers must consult their doctor before taking this medicine.

Also Read: Lowering Blood Sugar Level Naturally

  • Driving

It may cause vision problems. So, one should not drive or operate heavy machinery if you have any problems with your vision while using tenglyn 500 Tablet.

  • Liver

Tenglyn M 500 Tablet should be taken with caution in patients with liver diseases. The dose might have to be adjusted by your doctor.

  • Kidney

Tenglyn M 500 Tablet should be taken with caution, especially if you have a history of kidney diseases. The dose might have to be adjusted by your doctor.

Also Read: Reverse Diabetes Easily at Home

Diet & Lifestyle Advice

  • Half of your plate should be starchy vegetables, a quarter protein, and a whole quarter grain.
  • Consume food at regular intervals. Don’t take a big gap between meals or snacks.
  • Regularly check your blood sugar level, especially if there are a lot of swings.
  • Every week, commit to at least 150 minutes of moderate-intensity exercise and 15 minutes of high-intensity exercise.
  • To achieve a healthy body mass index, lose weight gradually (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with whole grain foods and increase fruits and veggies and other fiber-enriched foods.
  • Reduce saturated fat intake (or hidden fats) in crisps, chips, biscuits, pastries, and samosas. For everyday cooking, opt for omega-three fatty acid-rich oils. Palm oil, groundnut oil, mustard oil, rice bran oil, and safflower oil are all excellent options for frying.
  • Stress must be avoided because it can cause your blood sugar to rise. To control stress-related blood sugar variations, you can use stress management strategies like mindfulness, yoga, or meditation.
  • Reduce the amount of fat in your diet by choosing low-fat dairy products (low-fat yogurt, fat-free milk, cheese, etc.).
  • Maintain a normal blood pressure (120/80) as much as possible to lower the risk of heart disease in people with diabetes.

Also Read: Foods to Avoid While Taking Metformin

Important things that must be Remembered!


When one follows healthy lifestyle changes like weight loss, regular exercise, a healthy diet, and so on, tenglyn m 500 mg Tablet provides the best results.

Even when you think your blood sugar levels are under check, keep taking the medication. Do not double the dose if you miss a dosage; instead, get guidance from your treating physician.

When taking this medication, eat small, frequent meals and avoid fasting for long periods. Sweating, dizziness, palpitations, shivering, severe thirst, parched mouth, dry skin, frequent urination, and other hypoglycemia symptoms should be avoided. If you come across any of the symptoms listed above, eat 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar right away and contact your doctor. Make sure you have these on you at all times, especially if you’re going on a lengthy trip.

While taking this medication, avoid drinking alcohol since it raises the risk of hypoglycemia (low blood sugar, which can be fatal in some situations) and lactic acidosis (when the lactic acid increases in the body, which impacts various organs in the body).

Quit smoking and limit carbohydrate-rich foods such as potatoes, rice, mangoes, bread, sugar, etc.

Also Read: Glycomet gp2 Uses


What are the most common substitutes of tenglyn m 500?

Some of the most common substitutes of tenglyn m 500 are tenginow M Tablet SR, Met Janisha Tablet SR, Glipti Next M 500 Tablet SR, Vidglit-M Tablet SR, and Dynaglipt-M Tablet SR. However, one should not consume the substitutes of the medicine without consulting with their doctor.

Can there be any serious complications caused by tenglyn m 500?

In rare circumstances tenglyn m 500 can cause a highly serious complication known as lactic acidosis that is excess presence of lactic acid in the blood. If at any point the patient experience vomiting, rapid and deep breathing, stomach pain, and continuous nausea one should immediately consult their doctor.

What are salts present in the tenglyn m 500?

The salts present in tenglyn m 500 include Metformin and Teneligliptin. The composition of both salts include metformin salt is 500mg and the teneligliptin salt is 20 mg.

What is the working mechanism of tenglyn m 20 500?

The tablet Tenglyn M 20/500 keeps the blood sugar level in control by increasing the amount of insulin released by pancreas.

What is tenglyn m 500 used for?

Tenglyn M 500 SR tablet is used for controlling very high level of blood sugar in the body in case of type 2 diabetes. This tablet helps in preventing serious complications that can arise in case of diabetic patients, such as kidney damage and blindness in some cases.


  1. https://www.lybrate.com/medicine/tenglyn-m-500-tablet-sr
  2. https://www.zotezo.com/in/medicines/tenglyn-m-500-tablet/
  3. https://www.ndrugs.com/?s=tenglyn%20m
  4. https://www.1mg.com/drugs/tenglyn-m-500-tablet-sr-329626

Last Updated on by Dr. Damanjit Duggal 


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