Zomelis Met 50mg/500mg Tablet : Uses and Side Effect

Medically Reviewed By DR. SOUJANYA MANTHRIPRAGADA, MBBS, DNB(Family medicine) December 12, 2023

Living with type 2 diabetes requires a vigilant approach to managing blood sugar levels. One crucial ally in this journey is Zomelis Met 50mg/500mg Tablet—a potent combination of two medicines, Metformin (500mg) and Vildagliptin (50mg). This dynamic duo is designed to control high blood sugar levels and serve as a shield against the potential complications that diabetes can bring.

High blood sugar levels, a hallmark of diabetes, can wreak havoc on various organs and systems within the body. Zomelis Met 50mg/500mg tablet helps fight against the adverse effects of uncontrolled diabetes. By regulating blood sugar levels effectively, it plays a pivotal role in preventing serious complications such as kidney damage, blindness, and the ominous spectres of heart attacks or strokes.

Composition and Storage of Zomelis Met 50 500 mg

Zomelis Met 50mg/500mg tablet boasts a powerful blend of two key components—Metformin and Vildagliptin.

Metformin (500mg):

This widely recognised anti-diabetic medication belongs to the class of biguanides. It exerts its effects by reducing glucose production in the liver, slowing down glucose absorption from the intestines, and enhancing the body’s responsiveness to insulin.

Vildagliptin (50mg):

Serving as a DPP-4 inhibitor, Vildagliptin complements Metformin’s action by increasing insulin release from the pancreas. Additionally, it works to reduce hormones that elevate blood sugar levels. This dual mechanism of action helps achieve better control over both fasting and post meal sugar levels, contributing to more comprehensive diabetes management.

Storage Instructions:

Preserving the efficacy of Zomelis Met 50mg/500mg Tablet requires adherence to proper storage conditions. The recommended temperature for storage is below 30°C. Exposure to temperatures exceeding 30°C can compromise the stability of the medication. Whenever possible, it’s advisable to keep the tablets in their original packaging. The packaging is designed to provide an additional layer of protection against external factors that could compromise the medication’s quality.

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More About Zomelis Met 50mg/500mg Tablet for Type 2 Diabetes

Beyond its immediate role in blood sugar control, this medication plays a pivotal part in preventing potentially severe complications associated with diabetes, such as:

Controlling High Blood Sugar Levels:

By combining Metformin and Vildagliptin, this medication employs a synergistic approach to address the complex factors contributing to elevated blood glucose. The inclusion of Metformin, which reduces glucose production and enhances insulin sensitivity, along with Vildagliptin, which increases insulin release and reduces blood sugar-elevating hormones, makes this combination powerful enough to achieve optimal blood sugar control.

Preventing Complications:

It acts as a shield against the potential complications that untreated or poorly controlled diabetes can bring. Kidney damage, blindness, heart attacks, and strokes are among the serious complications that Zomelis Met aims to prevent. The importance of this prevention cannot be overstated, as these complications can significantly impact one’s quality of life and overall health.

Flexible Treatment Approach:

One notable aspect of Zomelis Met 50mg/500mg Tablet is its versatility in prescription. It can be prescribed as a standalone medication or in combination with other diabetes medications. This flexibility allows healthcare providers to tailor treatment plans to the unique needs of each individual. The effectiveness of Zomelis Met is enhanced when complemented by a healthy diet and regular exercise, highlighting the comprehensive nature of diabetes management.

Guidelines for Usage of Zomelis Met 50mg/500mg Tablet for Type 2 Diabetes

To reap the maximum benefits of Zomelis Met, it’s crucial to adhere to prescribed guidelines:

  • Consistent Daily Intake:

Taking the medication regularly, at the same time each day, is key to achieving optimal blood sugar control.

  • Mealtime Administration:

Taking Zomelis Met with meals is recommended to reduce the likelihood of developing an upset stomach. This consideration enhances the overall tolerability of the medication.

  • Medical Guidance:

The prescribed dose is contingent on individual factors such as overall health, blood sugar levels, and concurrent medications. Medical advice is paramount in determining the appropriate dosage for each individual.

  • Lifestyle Integration:

Zomelis Met is most effective when integrated into a holistic approach that includes a healthy diet and regular exercise. Lifestyle modifications play a pivotal role in diabetes management, and Zomelis Met complements these efforts.

Read More: Top 10 Homeopathic Medicine For Diabetes.

Common Side Effects of Zomelis Met:

Common Side Effects of Zomelis Met

Zomelis Met, while highly effective in controlling blood sugar levels, can occasionally lead to side effects. It’s important to note that most of these side effects are generally temporary and may resolve as the body adjusts to the medication. The most common side effects include:


Some individuals may experience changes in bowel habits, including diarrhoea.

Nausea and Vomiting:

Feeling nauseous or vomiting may occur, especially during the initial stages of medication.

Upset Stomach:

Discomfort or an upset stomach is a common side effect that typically diminishes with time.


Headaches are reported by some users and are often transient.

Sore Throat:

A sore throat may occur as a side effect, though it is not as commonly reported.


Some individuals may experience a sense of weakness or fatigue.

Gastroesophageal Reflux Disease (GERD):

GERD symptoms like heartburn and acid reflux can be observed.

Excessive Sweating:

Increased sweating may occur in some individuals as a side effect.

Decreased Appetite:

A temporary decrease in appetite is reported by some users.

Awareness of Hypoglycemia:

Apart from these common side effects, it’s crucial to be aware of the potential for hypoglycemia, especially when Zomelis Met is used in conjunction with other diabetes medications like insulin or sulfonylurea. Hypoglycemia, or low blood glucose levels, can manifest with symptoms such as trembling, headache, dizziness, nausea, weakness, increased sweating, and decreased appetite.

Read More: Chart of Normal Blood Sugar Levels

Monitoring and Managing Side Effects of Zomelis Met 50mg/500mg Tablet for Type 2 Diabetes

 Monitoring and Managing Side Effects of Zomelis Met

Before initiating Zomelis Met, it is imperative to disclose your complete medical history to your healthcare provider. The medication may not be suitable if you have a history of:

Kidney Disease:

Issues with kidney function may affect the way your body processes the medication.

Liver Disease:

Impaired liver function can impact the metabolism of the components in Zomelis Met.

Heart Disease:

Certain heart conditions may necessitate caution or alternative treatment options.

Pancreatic Problems:

Disorders related to the pancreas can influence how your body responds to it.

Alcohol Consumption:

Alcohol and diabetes management often don’t mix well. Consuming alcohol, especially in excessive amounts, can lower blood glucose levels. When combined with Zomelis Met, this can potentially lead to complications.

Medication Interactions:

Zomelis Met can interact with other medications, potentially affecting their efficacy or leading to unwanted side effects. To ensure your safety, it is crucial to inform your doctor about all the medications you are currently taking. This includes prescription medications, over-the-counter drugs, and even herbal supplements.

How to Use Zomelis Met Tablet

Follow the below given steps on how to use the Zomelis Met tablets:

Dosage and Duration Guidance from the Doctor:

The first and foremost step in using Zomelis Met Tablet is to follow the dosage and duration guidance provided by your healthcare provider. Your doctor will consider various factors such as your overall health, blood sugar levels, and any other medications you might be taking to determine the appropriate dosage.

Swallow It Whole:

Zomelis Met Tablet is designed to be swallowed whole. Do not chew, crush, or break the tablet. The formulation is optimised for gradual release, ensuring a sustained and controlled impact on blood sugar levels. Chewing, crushing, or breaking the tablet may interfere with this mechanism and compromise the effectiveness of the medication.

Take It with Food:

Zomelis Met 50mg/500mg Tablet should be taken with food. This enhances the absorption of the medication and helps reduce the likelihood of an upset stomach, which is a common side effect.

Read More: HbA1c (Hemoglobin A1c) A1c Chart, Test, Levels, & Normal Range

If you happen to miss a dose of Zomelis Met 50mg/500mg Tablet, here’s what you can do:

Take It as Soon as Possible:

If you realise that you’ve missed a dose, take it as soon as you remember.

Adjust Your Schedule:

However, if the time for your next scheduled dose is approaching, it might be best to skip the missed dose. Instead, wait for the next scheduled dose and resume your regular medication routine.

Do Not Double the Dose:

Do not double up on your medication to compensate for the missed dose. Doubling the dose can lead to an imbalance in blood sugar levels and may increase the risk of side effects.

The table below summarises the important properties of this medicine:

Brand Name Zomelis Met 50mg/500mg Tablet
Composition Metformin (500mg) + Vildagliptin (50mg)
Indicated For Treatment of Type 2 diabetes mellitus
Storage Conditions Store below 30°C
Dosage As advised by your doctor
Administration Swallow whole with food; Do not chew, crush, or break
Common Side Effects Diarrhoea, Nausea, Vomiting, Headache, Weakness, Gastroesophageal Reflux Disease, Increased Sweating, Decreased Appetite, among others
Advised Duration of Use As prescribed by the doctor
Habit Forming No
Therapeutic Class ANTI DIABETIC

FAQ’s( Frequently Asked Questions)

How does Zomelis Met Tablet help with Diabetes?

It controls high blood sugar levels, preventing complications like kidney damage and blindness. It may also reduce the risk of heart attack or stroke.

How do I take the Zomelis Met Tablet?

Swallow the tablet with food, as prescribed by your doctor, to reduce the chance of upset stomach.

Are there side effects of Zomelis Met Tablet?

Common side effects may include diarrhoea, nausea, vomiting, headache, weakness, and others. Consult your doctor if they persist.

Can Zomelis Met Tablet cause low blood sugar?

It’s unlikely on its own, but if you miss meals, drink alcohol, or take other diabetes medicines, it could.

Is Zomelis Met Tablet safe during pregnancy and breastfeeding?

Consult your doctor before using during pregnancy or breastfeeding, as it may have risks.

Can I drink alcohol while taking the Zomelis Met Tablet?

It’s unsafe to consume alcohol with this medicine.

What if I forget to take the Zomelis Met Tablet?

Take it as soon as possible. If it’s almost time for the next dose, skip the missed one. Don’t double the dose.

Is Zomelis Met Tablet habit-forming?

No, Zomelis Met Tablet is not habit-forming.

Can Zomelis Met Tablet cause Vitamin B12 deficiency?

Yes, with long-term use, it may interfere with Vitamin B12 absorption.

Last Updated on by Dr. Damanjit Duggal 


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