Bigomet SR 500 Tablet For Diabetes: Uses, Side Effects, Dosage & Interactions

Last updated on February 4th, 2022

Bigomet SR 500 Tablet is an anti-diabetic medication. It helps in regulating the levels of blood glucose. Hence, it prevents severe diabetes complications. Also, it helps treat menstruation-related disorders like polycystic ovary syndrome (PCOS) in females. Bigomet helps normalise the menstruation cycle. It restores the body’s hormonal balance, reduces glucose levels and promotes ovulation. Bigomet SR comprises Metformin hydrochloride as an active drug. It falls under the class of anti-diabetic drugs known as biguanides. Metformin:

  • decreases the glucose production by the liver
  • decreases the intestinal absorption of glucose
  • improves the insulin sensitivity.

Take Bigomet SR Tablet with food. This helps to avoid nausea and abdominal pain. A person must take it regularly to attain the maximum benefits. Also, the medication benefits when taken at the same time each day. A person must not stop taking this drug unless suggested by a doctor. Lifestyle plays a key role in diabetes control. Thus, a person must remain on the diet and exercise per the doctor’s recommendation. It is also important to monitor glucose levels while taking Bigomet.

Bigomet SR 500 treats type 2 diabetes when diet and exercise fail to control glucose levels. This medication is the first-line therapy for type 2 diabetics. Bigomet SR:

  • restores the body’s reaction to insulin
  • reduces the amount of blood sugar produced by the liver
  • delays the glucose absorption by the stomach or intestines.

Bigomet SR 500 acts best when combined with a healthy lifestyle. These lifestyle changes may include:

  • weight loss if a person is obese (BMI >25)
  • consumption of fewer calories (low-fat and sugary food)
  • physically active (at least 150 minutes of activity every week).

How Bigomet SR 500 Tablet works?

Metformin acts by decreasing the amount of glucose released by liver into the blood. Insulin works by reducing sugar production in the liver. It also reduces the glucose absorption from the intestine after consuming food. Also, it improves the sensitivity of the body organs and muscles towards insulin. As a result, Bigomet helps to control the blood glucose level.

Read More: Types of Insulin Chart

Uses of Bigomet SR 500 Tablet

Uses of Bigomet SR 500 Tablet

Treatment of type 2 diabetes. It is also known as non-insulin-dependent diabetes.

Benefits of Bigomet

Bigomet SR 500 plays a key role in:

  • Managing diabetes
  • According to the NHS, Bigomet helps attain control of blood glucose levels.
  • Delaying the absorption of glucose
  • Increasing the insulin sensitivity in the body

Bigomet SR 500 does not lead to a sudden lowering of the blood sugar level. Also, it does not cause significant hypoglycaemia. Bigomet does not cause weight gain, unlike other diabetes therapies. It may lead to a modest weight loss. In the prediabetic state, Bigomet is the most advisable treatment. The medication also aids in avoiding serious diabetes complications. These may include:

Bigomet SR also assists in lowering the chance of having a heart attack or stroke.

Read More: Know About Insulin Resistance to Prevent Type 2 Diabetes

Bigomet SR 500 Tablet Dosage and how to use?

  • The dose is the amount of the drug that exerts its therapeutic effect at that amount.
  • The initial dose of Bigomet SR is one tablet twice daily.
  • The correct dosage depends on the patient and the condition being treated.
  • Do not adjust the dose without the approval of a doctor.
  • Take the Bigomet SR tablet precisely as per the doctor’s instructions.
  • Consume the medication with or after a meal. It helps in avoiding the risk of side effects like digestion problems.
  • Avoid chewing or crushing the medicine. Swallow the tablet with a glass of water.

Read More: Top 10 Homeopathic Medicine For Diabetes.

Side effects of Bigomet SR 500 Tablet

The most common side effects that may occur with Bigomet SR are gastrointestinal (GI) complications. These include nausea, vomiting, or diarrhoea. According to a report by the National Institutes of Health, gastrointestinal problems occur in about 75% of people consuming metformin. A person can easily escape these problems if they take Bigomet with food. Side effects also tend to weaken over time. Bigomet may also result in side effects such as:

  • loss of appetite
  • abdominal pain, as stated by Frontiers
  • sour mouth taste
  • lactic acidosis (too much lactic acid in the blood).

Read More: How to Reverse Prediabetes Naturally?

Substitutes for Bigomet SR 500 Tablet

Medicine Brand Name Manufacturer
Mefomin 500 SR Tablet Macleods Pharmaceuticals Pvt Ltd
Glycomet 500 SR Tablet USV Ltd
Glyciphage SR 500mg Tablet Franco-Indian Pharmaceuticals Pvt Ltd
Gluconorm SR 500mg Tablet Lupin Ltd
Metsmall 500 Tablet SR Dr Reddy’s Laboratories Ltd
Riomet OD 500mg Tablet SR Sun Pharmaceutical Industries Ltd
Dibeta SR Tablet Torrent Pharmaceuticals Ltd
Xmet-SR Tablet Glenmark Pharmaceuticals Ltd
Walaphage -SR 500 Tablet Wallace Pharmaceuticals Pvt Ltd
Metadoze-IPR 500 Tablet SR Biocon
Metlong 500 Tablet SR Panacea Biotec Ltd
Sugamet SR 500 Tablet Zydus Cadila
Metaday 500 Tablet SR Wockhardt Ltd
Zomet SR Tablet Intas Pharmaceuticals Ltd
Recemin 500mg Tablet SR Bharti Life Sciences

Read More: 7 Day Meal Plan for Prediabetes

Bigomet SR 500 Interactions

Bigomet SR interacts with the following class of drugs. It alters its effectiveness:

  • Oral contraceptives
  • According to the NIH, Bigomet can interact with antifungals like Ketoconazole
  • NSAIDs (anti-inflammatory drugs)
  • Antibiotics like Rifamipicin
  • Corticosteroids such as Prednisolone
  • MAO inhibitors like Isocarboxazid
  • Diuretics like Hydrochlorothiazide, Furosemide

Bigomet SR reduces the blood sugar. Inform the concerned doctor about all other medications a person takes.

Contraindications of Bigomet SR 500 Tablet

  • According to the International Journal of Basic & Clinical Pharmacology, if you are hypersensitive to Metformin, do not take Bigomet SR.
  • If you ever had or have any heart or pituitary disease, do not take this drug.
  • Bigomet SR tablet is unsafe for a type 1 or insulin-dependent diabetes patient.
  • According to Diabetes UK, it’s crucial not to consume Bigomet if you drink alcohol excessively
  • Bigomet is also not safe for a patient with a history of heart disorders like stroke or heart attack.

Safety Advice

Safety advice for bigomet sr 500

  • It is wise to monitor blood pressure regularly.
  • People with serious kidney or liver dysfunction shouldn’t take Bigomet or Metformin tablets (as stated by the NIH).
  • People with a problem of heart failure must also avoid this medicine.
  • Do not take this drug if you have a history of liver or kidney disease. Monitor liver and kidney functions regularly.
  • According to BMC Geriatrics, it is not safe for people 80 or older as kidney function tends to decrease with age.
  • Avoid alcohol while consuming Bigomet SR 500.
  • Pregnant and breastfeeding females must not take this drug.
  • Patients with acute myocardial infarction must strictly avoid Bigomet.
  • Metabolic acidosis is excessive acid in the blood. Avoid consuming Bigomet 500 if a person has symptoms like headache or vomiting. It might worsen the condition.
  • Bigomet might not be effective in regulating the blood glucose level in people with type 1 diabetes, as stated by the Mayo Clinic. Insulin injections are essential to treat such conditions.
  • Bigomet SR is not safe for use under stress-inducing conditions. These may include fever, trauma, operations, or accidents. Discuss continuing this drug with a doctor in such cases.
  • Bigomet 500 mg is not safe for use in children. Since, the safety and efficacy data is not available.
  • The possibilities of weight gain and low blood glucose are smaller with Bigomet than with other diabetes drugs.
  • Hypoglycemia might occur when given with other diabetes drugs, alcohol or on missing a meal. Carry a glucose source for instant relief.
  • Bigomet tablet might also result in a rare and serious condition called lactic acidosis. It is an excess of lactic acid in the blood.

Read More: Key Differences Between Diabetologists And Endocrinologists?

Overdose of Bigomet SR

Overdose of Bigomet SR

Too much intake of Bigomet SR may lead to vitamin B12 deficiency. And, this might result in:

  • Anemia
  • Fatigue
  • Pale skin
  • Headache
  • Breathing problems.

Missed dose

If you miss a dose of this tablet, consume it as soon as possible. Consider omitting the missed dose if it is time for the next dosage. Never consume two doses to make up for a skipped one.

Read More: Insulin Resistance Diet: What to Eat & What to Avoid

Diet & Lifestyle Precautions

  • Do a minimum of 150 minutes of moderate-intensity physical activity every week. Or, a person can do 75 minutes of high-intensity exercise each week.
  • Lose weight progressively to attain a healthy BMI (18.5 to 24.9).
  • Replace refined carb-containing foods with whole-grain foods. Also, increase the intake of fruits, veggies and other fiber-enriched foods.
  • Avoid excessive stress. It might increase a person’s blood glucose level. To control stress-related blood glucose changes, a person can practice certain stress management techniques, such as mindfulness, yoga, or meditation.
  • Keep the blood pressure within normal limits, i.e., 140/90. It decreases the risk of cardiovascular disorders in diabetes patients.


Can a breast-feeding mother take Bigomet?

Taking Bigomet is considered safe in case of breastfeeding. This would not affect the infant.

Can Bigomet be given to a pregnant female?

Bigomet tablet is generally not advised during pregnancy. Since, it may exert significant side effects on the foetus. Yet, doctor might suggest a safer option with similar therapeutic effect based upon the clinical condition.

Is Bigomet SR a habit-forming drug?

No, it is not an addictive medication.

How long does the effects of Bigomet last?

Bigomet 500 mg stays active in body for nearly 4 days.

How long does it take for Bigomet SR 500 to take effect?

The time duration required for Bigomet to exert its effects is roughly 7 to 8 hours after its intake.

Last Updated on by Dr. Damanjit Duggal 


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