Glycomet Tablet: Uses, Dosage, Precautions, Side Effects

Medically Reviewed By Dr. Subhanshu Gupta, MBBS, MD, 11 Years of Experience January 24, 2024

What is Glycomet?

Glycomet GP1 (or other form of Glycomet) is a medication that is commonly prescribed for the management of type 2 diabetes. According to PubMed Central’s 2014 Medical report, glycomet is more specifically used for type 2 diabetes with obesity. It is an oral antidiabetic drug that helps control blood sugar levels in individuals with this condition. It falls under the class of drugs known as biguanides. The active ingredient in Glycomet GP1 is Metformin hydrochloride. Glycomet is available in various forms, like immediate-release tablets, extended-release tablets, and oral solutions.

Diabetes worsens over time, but taking care of your lifestyle can help you avoid taking more medication. Studies show that structured lifestyle management is the best way to reverse diabetes, control blood sugar, and avoid long-term complications.

Glycomet Tablet Uses

Glycomet Tablet Uses , glycomet gp2 , glycomet 500

The primary purpose of Glycomet GP1 is to effectively manage type 2 diabetes. Here are some Glycomet tablet uses:

Type 2 Diabetes

The primary Glycomet tablet uses involve the treatment of type 2 diabetes, where blood sugar levels are difficult to control with lifestyle changes. It helps improve insulin sensitivity and control blood sugar levels. Glycomet tablet uses include the first-line treatment for type 2 diabetes, either alone or in combination with other antidiabetic medications. According to a review published in Lybrate Medicine, glycomet helps improve peripheral glucose disposal and insulin resistance. It reduces the risk of complications associated with high blood sugar levels.

Blood Sugar Control

Glycomet GP1 uses include reducing the amount of glucose produced by the liver and increasing the body’s sensitivity to insulin. This helps lower and stabilize blood sugar levels, ensuring they remain within the target range for individuals with type 2 diabetes.

Gestational Diabetes

In some cases of gestational diabetes, Glycomet GP1 may be prescribed to pregnant women. The medicine helps manage blood sugar levels and reduces the risk of complications for both the mother and baby. According to New Zealand’s Health Ministry, Glycomet is completely safe and recommended by doctors to be used in gestational diabetes.

Polycystic Ovary Syndrome (PCOS)

Glycomet tablet uses extend to the management of polycystic ovary syndrome, a hormonal disorder affecting women of reproductive age. It helps regulate menstrual cycles, reduce insulin resistance, and lower androgen levels. According to an NIH(National Institute of Health) study, glycomet is a very effective medicine to induce ovulation in women suffering from PCOS.

It’s worth noting that Glycomet should be used as part of a comprehensive diabetes management plan, which includes lifestyle modifications such as a healthy diet, regular exercise, weight management, and regular blood sugar monitoring. The dosage and duration of treatment will be determined by a healthcare professional based on individual needs and response to the medication.

Read More: Best Diabetes Diet Plan – Dietary Guidelines For Diabetic Patients

Glycomet Dosage For Diabetes

The ideal Glycomet dose (metformin) for diabetes may vary depending on several factors, including the individual’s medical condition, blood sugar levels, response to treatment, and other medications being taken. Glycomet dosage is typically determined by a healthcare professional and should be followed as prescribed.

In general, the initial recommended Glycomet dose for adults is usually 500 mg or 850 mg, taken orally once or twice a day with meals. The dosage may be adjusted gradually based on blood sugar control and tolerance, with a maximum daily dose of 2,550 mg.

For extended-release formulations, the initial recommended dose is often 500 mg or 1,000 mg, taken orally once daily with the evening meal, and the Glycomet dosage can be adjusted gradually if needed.

It’s important to note that individual requirements may vary, and the Glycomet dosage should be determined by a healthcare professional who will consider various factors specific to each patient. Regular monitoring of blood sugar levels, along with follow-up appointments with the healthcare provider, is crucial to evaluate the effectiveness of the medication and make any necessary dosage adjustments.

Glyomet Weekly Dosage

  Breakfast Lunch Dinner
Week 1-2 500 mg
Week 3-4 500 mg 500 mg
Week 5-6 500 mg 500 mg 500 mg

The recommended Metformin dose in the case of extended-release tablets is 500 mg once daily, taken with the evening meal. Moreover, according to the National Institute of Health, the maximum recommended dose is 2000 mg/day, taken in two divided doses. Extended-release metformin is meant to show its effect slowly over time, so it’s important not to crush, chew, or break the tablet.

However, it is essential to note that Metformin dosage for diabetes should be individualized based on the patient’s response and tolerance to the medication. Patients with kidney or liver problems or who are elderly may require lower doses of metformin. Therefore, it is important to consult a healthcare provider who can determine the appropriate Metformin dosage for diabetes as per the patient’s needs.

Glycomet Composition

Glycomet is a brand name for the medication metformin hydrochloride, which is used to treat type 2 diabetes. The active ingredient in Glycomet 500 composition is metformin hydrochloride, which is a white crystalline powder that is soluble in water.

In addition to the active ingredient, Glycomet composition also includes a number of inactive ingredients that help to bind the tablet together and facilitate its absorption in the body. These inactive ingredients may vary depending on the specific formulation of the medication and the manufacturer, but common Glycomet composition includes microcrystalline cellulose, povidone, magnesium stearate, and hypromellose.

It is important to note that if you have any allergies or sensitivities to any of the ingredients in Glycomet, you should consult with your healthcare provider before taking this medication.

Directions For Use

The directions for using Glycomet GP1 (or other metformin medicine) should be followed as prescribed by your healthcare professional. Here are some general guidelines for the use of Glycomet GP1:

Step 1:

Ensure you swallow the tab Glycomet intact with water and avoid crushing, chewing, or breaking them unless specifically instructed by your doctor.

Step 2:

Maintain a consistent daily schedule for taking the Glycomet GP1 tablets to keep your blood sugar levels stable.

Step 3:

In case you miss a dose, adhere to your regular dosing schedule, but if you’re uncertain, seek advice from your doctor or pharmacist.

Step 4:

It is important not to discontinue the use of tab Glycomet without consulting your doctor, as this can result in a sudden surge in blood sugar levels.

Read More: Can Type 2 Diabetes be Reversed Permanently?

Glycomet Contraindications

Glycomet GP1 may have contraindications or situations where its use is not recommended. It is important to consult with a healthcare professional for personalized advice. Here are some common contraindications associated with Glycomet GP1:

Renal Impairment

Sugar tablets Glycomet like Glycomet GP1, Glycomet gp 0.5 and others should be used with caution or avoided in individuals with significant renal (kidney) impairment or dysfunction. This is because the drug’s components are primarily eliminated through the kidneys, and impaired renal function can increase the risk of drug accumulation and potential side effects.

Hepatic Impairment

According to Lybrate Health, Individuals with severe liver and kidney disease or hepatic impairment may have difficulty metabolizing and clearing metformin from their system. As a result, the use of Glycomet GP1 may be contraindicated or require careful monitoring in such cases.

Allergy or Hypersensitivity

People who are allergic or have hypersensitivity to metformin or any of the other components of Glycomet GP1 should avoid it.

Severe Infections

During periods of severe infections or illnesses, the use of tab Glycomet like Glycomet SR 500 or Glycomet GP1 may need to be temporarily discontinued. This may be due to the potential risk of developing lactic acidosis, a rare but serious side effect associated with the medicine.

Pregnancy and Breastfeeding

The use of Glycomet GP1 during pregnancy and breastfeeding is a matter that should be discussed with a healthcare professional. Generally, tab Glycomet, like Glycomet GP1, is not recommended during pregnancy, and the decision to use it while breastfeeding should be made considering the potential risks and benefits.

Contrast Agents

If you are scheduled for a procedure involving the use of contrast agents (such as certain imaging tests), it is important to inform your healthcare provider about your use of Glycomet GP1 or any other tablet. In some cases, the medication may need to be temporarily discontinued to reduce the risk of kidney problems.

It’s important to consult your healthcare provider doctor regarding your ongoing medications and medical conditions before starting metformin.

Read More: 15 Foods To Lower Blood Sugar Levels


Glycomet Precautions , glycomet 500 precaution

While taking Glycomet GP1 or any other tablet of Glycomet, it is important to follow certain precautions to ensure safe and effective use of the medication. Here are some precautions to consider:

Consultation with a Healthcare Professional

Always consult with your healthcare advisor before starting Glycomet GP1 or making any changes to your medication regimen. They can provide personalized guidance based on your medical history, current condition, and other medications you may be taking.

Kidney Function Monitoring

Regular monitoring of kidney function is essential while taking any Glycomet medicines like Glycomet GP1. According to a report from NIH (National Institute of Health), kidney patients should completely avoid glycomet. Inform your doctor if you have any kidney problems or if you experience symptoms such as decreased urine output or swelling in the legs.

Avoid Alcohol

Alcohol consumption can increase the risk of lactic acidosis, a serious side effect associated with Glycomet GP1. It is advisable to avoid or limit alcohol intake while taking the medication.

Hypoglycemia Awareness

Glycomet GP1 primarily helps lower blood sugar levels. Be aware of the signs and symptoms of low blood sugar (hypoglycemia), such as sweating, dizziness, confusion, and hunger. Carry a source of fast-acting glucose, such as glucose tablets or candy, to treat hypoglycemic episodes if they occur.

Surgical Procedures

If you are scheduled for surgery or any medical procedure, inform your healthcare provider about your use of Glycomet GP1. They may advise temporarily discontinuing the medication before the procedure to reduce the risk of complications.

Monitoring Vitamin B12 Levels

Long-term use of Glycomet may be associated with vitamin B12 deficiency. Moreover, studies published by NIH (National institute of Health) also established a relationship between long-term Glycomet usage and vitamin B12 deficiency. Your doctor may monitor your vitamin B12 levels periodically and recommend supplementation if necessary.

Stay Hydrated

Ensure adequate hydration, especially during periods of illness, fever, or dehydration, as these conditions can increase the risk of lactic acidosis.

Inform Other Healthcare Providers

Make sure to inform other healthcare providers, such as dentists or specialists, about your Glycomet tablet uses, as it may interact with certain medications or procedures.

Remember, these precautions are general guidelines, and it’s important to consult with a doctor for personalized advice based on your specific situation. They will provide you with the necessary precautions and recommendations for safe and effective Glycomet tablet uses.

Read More: What is Glycemic Index And To Calculate?

Glycomet Side Effects

Glycomet Side Effects , glycomet sr 500 side effects , glycomet gp1 side effects

Glycomet (metformin) may cause certain side effects, although not everyone experiences them. It’s important to note that the severity and occurrence of Glycomet side effects can vary among individuals. Here are some common side effects associated with Glycomet:

Gastrointestinal Issues

The most common Glycomet SR 500 side effects are related to the gastrointestinal system. These can include diarrhea, nausea, vomiting, abdominal discomfort, bloating, and a metallic taste in the mouth. These symptoms are usually mild and transient, and they can be minimized by taking Glycomet with meals.


Hypoglycemia is one of the common Glycomet side effects. When Glycomet is used alone, it typically does not cause hypoglycemia (low blood sugar). However, if taken in combination with other antidiabetic medications or insulin, it may increase the risk of hypoglycemia. Symptoms of hypoglycemia include sweating, dizziness, confusion, irritability, and weakness.

Vitamin B12 Deficiency

According to a 2016 study by the Journal of Clinical Endocrinology & Metabolism, long-term use of Glycomet may lead to certain Glycomet side effects like vitamin B12 deficiency. This can result in symptoms such as fatigue, weakness, tingling or numbness in the extremities, and anaemia. Regular monitoring of vitamin B12 levels may be necessary, and supplementation may be recommended if deficiency is detected.

Lactic Acidosis (Rare)

Lactic acidosis is one of the rare but serious Glycomet SR 500 side effects. This is more particularly in individuals with impaired kidney function or other predisposing factors. Symptoms may include muscle pain, difficulty breathing, abdominal discomfort, dizziness, and irregular heartbeat. Seek immediate medical attention if you experience any of these symptoms.

Other Side Effects

Less common Glycomet side effects can include skin reactions (such as rash or itching), changes in taste, reduced vitamin B12 absorption, and elevated levels of liver enzymes.

It is important to report any side effects to your diabetologist. They can provide guidance on managing side effects or adjust the dosage if necessary. Do not discontinue Glycomet without consulting your doctor. They will weigh the benefits of the medication against the potential risks and side effects specific to your condition.

Interactions of Glycomet

Tab Glycomet (metformin) can interact with other medications, substances, or medical conditions, potentially affecting its effectiveness or causing adverse effects. It’s important to inform your healthcare professional about all the medications, supplements, and herbal products you are taking. Here are some common interactions associated with Glycomet:

Medications that Increase the Risk of Lactic Acidosis

Certain medications can increase the risk of developing lactic acidosis when used in combination with Glycomet GP1. These may include drugs such as certain diuretics (e.g., furosemide), nonsteroidal anti-inflammatory drugs (NSAIDs), ACE inhibitors, and alcohol. Inform your doctor about all the medications you are taking to minimize the risk of lactic acidosis.

Medications that Affect Kidney Function

Drugs that can impair kidney function may increase the risk of metformin accumulation in the body, potentially leading to adverse effects. Examples include some antibiotics (e.g., ciprofloxacin), certain antiviral drugs (e.g., ritonavir), and contrast agents used in imaging procedures. Your healthcare provider will evaluate the risks and benefits of using tab Glycomet like Glycomet GP1, in combination with these medications.

Medications that Lower Blood Sugar Levels

Combining Glycomet GP1 or any other sugar tablets Glycomet with other antidiabetic medications (e.g., insulin, sulfonylureas) can increase the risk of hypoglycemia (low blood sugar). Regular blood sugar monitoring is crucial in such cases, and dosage adjustments may be necessary.

Iodinated Contrast Agents

Iodinated contrast agents used in certain imaging procedures can potentially cause kidney problems. If you are scheduled for such a procedure, inform your doctor about your use of Glycomet. As they may recommend temporarily discontinuing the medication before the procedure.


Alcohol consumption while taking Glycomet GP1 can increase the risk of lactic acidosis. This may interfere with your blood sugar control. It is generally advised to limit or avoid alcohol intake. According to the Medical News Today website, one can only consume light to moderate amounts of alcohol (occasionally) while taking Glycomet.

These are not exhaustive lists of interactions. Always consult your healthcare professional for a comprehensive assessment of potential interactions based on your specific medications and medical history. They can provide guidance on how to manage potential interactions or adjust the dosage if necessary.

Read More: What Are The Top 10 Early Signs And Symptoms Of Diabetes?

Overdose of Glycomet

Overdose of Glycomet, glycomet sr 500 twice a day

Taking an overdose of Glycomet (Metformin) can potentially lead to serious side effects and complications. It is important to always follow the dosage prescribed by your doctor.

An overdose of Glycomet GP1 can cause an excessive decrease in blood sugar levels (hypoglycemia), which can result in symptoms such as:

  • Sweating
  • Shakiness or tremors
  • Dizziness or lightheadedness
  • Confusion or difficulty concentrating
  • Blurry vision
  • Headache
  • Weakness or fatigue
  • Pale skin
  • Irregular heartbeat
  • Loss of consciousness or seizures (in severe cases)

If you suspect that you have taken an overdose of Glycomet GP1 or any other form of Glycomet, or if you are experiencing symptoms of hypoglycemia (low blood sugar), it is important to seek immediate medical attention. You can call emergency services or go to the healthcare provider for evaluation and treatment. It’s worth noting that the specific symptoms and severity of an overdose can vary from person to person. The risk of an overdose is higher in individuals with impaired kidney function or other medical conditions that affect the clearance of Metformin from the body. It’s always best to follow your doctor’s guidance and adhere to the prescribed dosage to ensure the safe and effective use of any medication.

FAQs (Frequently Asked Questions)

What is a Glycomet tablet used for?

Tab Glycomet, like Glycomet 500, Glycomet SR 500, or Glycomet GP1, are primarily used for the management of type 2 diabetes. They contain the active ingredient metformin and help regulate blood sugar levels by improving insulin sensitivity and reducing glucose production in the liver. This medication is often part of a comprehensive approach that includes diet, exercise, and lifestyle modifications. It is important to follow the prescribed dosage and recommendations provided by your healthcare professional for optimal diabetes management.

Are Glycomet and Metformin the same?

Yes, Metformin and Glycomet are essentially the same medication. Glycomet is a brand name for the generic drug metformin hydrochloride. Metformin is the active ingredient found in Glycomet tablets like Glycomet GP1 or Glycomet SR 500. Both Metformin and Glycomet have the same pharmacological effects and are used for the management of type 2 diabetes. The choice between the generic metformin and the brand name Glycomet may depend on availability, pricing, and personal preference, but their medical properties are equivalent. It’s always important to consult with your healthcare professional for guidance on using specific medications.

Which class is Glycomet?

Glycomet belongs to the class of medications known as biguanides. Specifically, it contains the active ingredient metformin hydrochloride, which falls under the biguanide class of drugs. Biguanides work by reducing glucose production in the liver. Thereby improving insulin sensitivity in the body, and enhancing the uptake and utilization of glucose by cells.

How effective is Glycomet?

Glycomet (metformin) is considered an effective medication for the management of type 2 diabetes. When used as prescribed and combined with appropriate lifestyle modifications, this tab Glycomet can effectively lower blood sugar. However, the effectiveness of Glycomet GP1 can vary among individuals due to different factors. These include overall health, adherence to treatment, and individual response to the medication. All these factors can influence its effectiveness.

How long does it take for Glycomet to work?

Glycomet is a medication commonly used to treat type 2 diabetes. The time it takes for Glycomet GP1 to work can vary depending on several factors. These include the individual’s metabolism, dosage, and overall health condition.
In general, Glycomet typically starts showing its effects after 3 hours. However, the full therapeutic benefits may take several weeks to manifest. It is important to note that Glycomet GP1 is typically prescribed as a long-term medication. It helps manage blood sugar levels rather than providing immediate relief.
It’s crucial to follow your diabetologist’s instructions regarding Glycomet dosage and timing. Only your doctor can prescribe the best dose of glycomet for you after analysing your prevailing health condition.

Which is better, Glycomet or Glycomet SR?

Both Glycomet and Glycomet SR are formulations of the medication metformin used for the treatment of type 2 diabetes. The key difference between them lies in their release profiles. Glycomet is an immediate-release formulation that is absorbed quickly into the bloodstream. While Glycomet SR (sustained-release) is designed to release the medication gradually over an extended period. This slower release helps maintain more stable blood sugar levels throughout the day. The choice between Glycomet and Glycomet SR depends on individual needs and preferences.

What is the brand name of Glycomet?

Glycomet itself is a commonly used brand name for the medication metformin. Glycomet is manufactured by USV Ltd., an Indian pharmaceutical company. It is important to note that there might be other brand names for metformin available in India. Different pharmaceutical companies may market metformin under different brand names. It is always advisable to consult with your diabetologist. They will ensure you have the correct brand name and formulation.

Does Glycomet tablet help in weight loss?

Glycomet, or metformin, is primarily prescribed as an antidiabetic medication to help manage blood sugar levels in individuals with type 2 diabetes. While weight loss can be a potential side effect of Glycomet. It is not its primary purpose or indication. However, some diabetics taking Glycomet may experience weight loss. This may be a result of improved blood sugar control, decreased appetite, or other metabolic effects.
It is important to note that the extent of weight loss can vary among individuals. Metformin alone is not typically prescribed as a weight loss medication. If weight loss is a specific goal, it is recommended to discuss appropriate strategies with your doctor.

Does Glycomet cause acidity?

Glycomet (metformin) is not known to directly cause acidity or increase stomach acid production. While gastrointestinal side effects like nausea or stomach upset are possible, they are generally mild and temporary. Some individuals may experience acid reflux or indigestion. But these Glycomet side effects often improve over time as the body adjusts. It is advised to take metformin with food to minimize gastrointestinal discomfort. If you have persistent or severe acidity or other concerning side effects, consult your doctor for evaluation and guidance.

When should I take Glycomet morning or evening?

The timing of tab Glycomet intake can vary depending on individual circumstances and the instructions provided by your healthcare professional. In general, Glycomet is often taken with meals to minimize gastrointestinal side effects. However, specific recommendations may differ based on factors such as your medication dosage, lifestyle, and personal preferences. It is advisable to follow the guidance of your doctor regarding the timing and dosage of tab Glycomet. They can provide tailored instructions based on your specific needs and help optimize the effectiveness and tolerability of the medication.

Which diabetes medicine is safest?

When it comes to diabetes medications, safety considerations depend on individual factors and should be determined by a healthcare professional. Several diabetes medications, including Glycomet GP1, are generally considered safe when used as prescribed. Glycomet GP1 is widely prescribed due to its long-standing safety profile, effectiveness in blood sugar control, and low risk of hypoglycemia.
Other commonly used diabetes medications in India include gliclazide, voglibose, and pioglitazone, which also have established safety records. However, the choice of medication should be based on various factors like the patient’s specific health condition, medical history, and any potential drug interactions.

Is Glycomet banned in India?

Glycomet (metformin) is not banned in India, while another diabetes medicine called Pioglitazone was banned back in 2013, which is totally unrelated to Glycomet. Glycomet GP1 is a widely used and commonly prescribed medication for the treatment of type 2 diabetes. However, it’s important to note that regulations and availability of medications can change over time, so it’s always advisable to consult with a healthcare professional before buying any medication.

Can we tale Glycomet twice a day?

The dosing schedule for Glycomet (metformin) can vary depending on individual factors and the recommendations of a healthcare professional. In some cases, tab Glycomet like Glycomet GP1 may be prescribed to be taken twice a day. However, it is crucial to follow the specific instructions provided by your doctor.

They will consider factors such as your medical condition, blood sugar control, and other medications you may be taking. Taking Glycomet as directed is important for achieving optimal results and avoiding potential side effects.

Can I stop taking Glycomet?

It is important to note that decisions regarding the continuation or discontinuation of Glycomet (metformin) should be made in consultation with a healthcare professional. Glycomet GP1 is often prescribed for the long-term management of type 2 diabetes. Abruptly stopping Glycomet GP1 without medical guidance can lead to uncontrolled blood sugar levels and potential complications. Your healthcare advisor will consider various factors, such as your current health status, blood sugar control, and any other medications you are taking, before making recommendations about modifying or discontinuing Glycomet GP1. It is crucial to have an open discussion with your healthcare professional to determine the most appropriate course of action for your specific situation.

Last Updated on by Dr. Damanjit Duggal 


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